Open AccessNot Otherwise Specified-Type Sarcoma of Breast with CD10 Expression: Case Report
Author(s) -
Bermal Hasbay,
Fılız Bolat,
Hülya Aslan,
Hüseyin Özgür Aytaç
Publication year - 2019
Publication title -
meme sağlığı dergisi/meme sağlığı dergisi
Language(s) - English
Resource type - Journals
eISSN - 1306-0953
pISSN - 1306-0945
DOI - 10.5152/ejbh.2019.4295
Subject(s) - leiomyosarcoma , undifferentiated pleomorphic sarcoma , angiosarcoma , medicine , sarcoma , immunohistochemistry , pathology , liposarcoma , rhabdomyosarcoma , malignant peripheral nerve sheath tumor , not otherwise specified , soft tissue sarcoma , fibrosarcoma
Primary breast sarcomas are very rare and account less than 1% of invasive breast carcinomas. Primary sarcomas of breast are leiomyosarcoma, angiosarcoma, liposarcoma, fibrosarcoma, rhabdomyosarcoma, malignant peripheral nerve sheath tumor and pleomorphic sarcoma. Recently, a new CD10 positive group of sarcoma was identified. These tumors cannot be classified as a soft tissue sarcoma and show diffuse strong positive staining pattern with CD10 (NSCD10). Herein we report clinical and morphological characteristics of two cases diagnosed with not otherwise specified-type sarcoma with CD10 expression by histologically and immunohistochemical findings with the literature. NSCD10 shows similarity with leiomyosarcoma and sarcomatoid-type metaplastic carcinoma histomorphologically among specific sarcomas of breast. CD10 expression should be taken into consideration in the presence of not diagnosed and not specified tumors and CD10 should be added to the immunohistochemical panel.