Open AccessThe Effects of Dexmedetomidine on Ischemia Reperfusion Injury in Patients Undergoing Arthroscopy Under Spinal Anesthesia
Author(s) -
Senem Koruk,
Ayşe Mızrak,
Recai Kaya,
Bakiye Uğur,
Oğuz Cebesoy,
Ahmet Çelik,
Öner Ünsal
Publication year - 2010
Publication title -
the eurasian journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.337
H-Index - 13
eISSN - 1308-8742
pISSN - 1308-8734
DOI - 10.5152/eajm.2010.38
Subject(s) - dexmedetomidine , medicine , anesthesia , tourniquet , hemodynamics , ketamine , malondialdehyde , reperfusion injury , ischemia , sedation , oxidative stress
Ischemia and reperfusion injury due to tourniquet application during arthroscopy is a well known problem. This study aimed to compare the effects of dexmedetomidine and ketamine on hemodynamic and respiratory variables and on total anti-oxidant status (TAS), total oxidant status (TOS) and malondialdehyde (MDA) as markers of ischemia-reperfusion injury.