Open AccessComparison of PD-L1, EGFR, ALK, and ROS1 Status Between Surgical Samples and Cytological Samples in Non-Small Cell Lung Carcinoma
Author(s) -
Rahmi Gökhan Ekin,
Denız Nart,
Pınar Savaş,
Alı Veral
Publication year - 2021
Publication title -
balkan medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.398
H-Index - 16
eISSN - 2146-3131
pISSN - 2146-3123
DOI - 10.5152/balkanmedj.2021.20086
Subject(s) - ros1 , medicine , anaplastic lymphoma kinase , lung cancer , cytology , histology , epidermal growth factor receptor , pathology , biopsy , adenocarcinoma , cancer , malignant pleural effusion
The expression levels of Programmed death ligand-1 (PD-L1), epidermal growth factor receptor (EGFR), anaplastic lymphoma tyrosine kinase gene (ALK), and proto-oncogene tyrosineprotein kinase 1 ROS (ROS1) are important for targeted treatment selection in advanced lung cancer. Most patients with lung cancer are diagnosed at an advanced stage and have no chance of surgery. For this reason, the accuracy and reliability of cytology samples for detecting those markers is important in patients whose histological sampling cannot be performed.