Open Access
The Phytochemical Investigation and Biological Activities of <em>Berberis Orthobotrys</em>
Author(s) -
Dad Akber,
Iftikhar Ali,
Nadja Engel,
Muhammad Atif,
Hidayat Hussain,
Viqar Uddin Ahmad,
Peter Langer,
Ivan R. Green
Publication year - 2017
Publication title -
international journal of phytomedicine
Language(s) - English
Resource type - Journals
ISSN - 0975-0185
DOI - 10.5138/09750185.1899
Subject(s) - fusarium solani , phytochemical , chemistry , stereochemistry , biology , horticulture , biochemistry
The leaf extract of Berberis orthobotrys Bien. ex Aitch. (B.o.) afforded three compounds viz., β-sitosterol ( 1 ), sesamin ( 2 ) and 10-eicosanol ( 3 ) which were identified by spectroscopic methods including 1D and 2D NMR, GC-MS, IR and comparison of their spectral data with the published data. To the best of our knowledge these three compounds are reported here for the first time to be isolated from Berberis orthobotrys Bien. ex Aitch. (B.o.). Moreover the root extract exhibited good antilieshmanial activity and root and fruit extracts demonstrated minor antifungal activity against Fusarium solani .