Open AccessTumor de células de la granulosa juvenil de ovario. Presentación inusual. Reporte de un caso
Author(s) -
Ernesto Lara,
Franco Calderaro Di Ruggiero,
Cármen Silva,
Johatson Freytez
Publication year - 2021
Publication title -
revista de obstetricia y ginecología de venezuela
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.11
H-Index - 8
ISSN - 0048-7732
DOI - 10.51288/00810113
Subject(s) - medicine , ovary , pathological , immunohistochemistry , stromal tumor , pathology , ovarian tumor , gynecology , stromal cell , ovarian cancer , cancer
Granulose cell tumors represent 2% of ovarian tumors. They are classified as adult type and juvenile type. The juvenile type is associated with precocious pseudopuberty, irregular menstruation or nonspecific symptoms such as abdominal pain and palpable mass. More than 95% are confined to the ovary. A case of a 31-year-old patient is described. The patient consulted for 6-month evolution of increased abdominal volume and weight loss. Right ovary tumor was diagnosed. Tumor excision by gynecological laparotomy with positive frozen cut biopsy and surgical staging were performed. Pathological anatomy reported stromal tumor, and sexual cords suggestive of malignant juvenile granulose cell tumor. Immunohistochemistry reported positive inhibin B. It was concluded as stage IIIA2. This is a rare neoplasm with variable behavior. Accurate diagnosis is based on histological and immunohistochemical studies. Key words: Granulosa, Cell tumor, Juvenile granulosa cell tumor, Ascites, Diagnosis.