Open AccessFrequency of Hepatitis A & E Infections in Adult Patients of Acute Hepatitis
Author(s) -
Rukhsana Gulzar,
Rehma Dar,
Qurat Ul Ain,
Humair Ahmad,
Syed Salman Ali,
Hira Sajjad
Publication year - 2020
Publication title -
esculapio
Language(s) - English
Resource type - Journals
eISSN - 2309-592X
pISSN - 2309-3080
DOI - 10.51273/esc20.2516318
Subject(s) - medicine , hepatitis a , hepatitis e virus , coinfection , hepatitis , acute hepatitis , hepatitis e , virology , viral hepatitis , hepatitis a virus , virus , immunology , biology , genotype , biochemistry , gene
Objective: To study the frequency of Hepatitis A Virus and Hepatitis E Virus infections in adult patients of acute hepatitis in a Tertiary Care Hospital in Lahore. Methods: All samples received from medical units (indoor and outdoor) of Mayo hospital Lahore from 26 Feb.2019 to 26.Sept.2019, for Hepatitis A & E IgM antibody testing by ELISA were included in the study. The results and other relevant information were recorded on proforma. Results: Out of 690 study subjects, 62% were male and 38% were female. The mean age ± SD was 33.8 + 7.4years. The percentage of HAV or HEV infected cases was 59%,and 41% were not infected with HAV or HEV. The frequency and percentage of Hepatitis AVirus was 62(15%),whereas the frequency and percentage of HEV was 327(80%) and that of co-infection with HAV and HEV was 21(5%). The mean + SD age of Hepatitis AVirus was 35.2 + 5.0,whereas the mean + SD age of Hepatitis E Virus and co-infection with Hepatitis A and Hepatitis E Virus were 31.45 + 2.3 and 22.6 + 6.3 years, respectively. Conclusion: Hepatitis E Virus is the commonest cause of acute hepatitis in our study,followed by hepatitis A Virus and coinfection of HAV and HEV. Key words: Frequency, Hepatitis A infection, Hepatitis E infection, Co- infection Hepatitis A & Hepatitis E.