Open AccessInvestigation of Some Trace Element Levels in Multiple Sclerosis
Publication year - 2021
Publication title -
kastamonu tıp dergisi (katid)
Language(s) - English
Resource type - Journals
ISSN - 2757-9336
DOI - 10.51271/kmj-0001
Subject(s) - zinc , oxidative stress , trace element , multiple sclerosis , medicine , iron status , chemistry , inductively coupled plasma mass spectrometry , homeostasis , gastroenterology , pathology , immunology , iron deficiency , chromatography , mass spectrometry , organic chemistry , anemia
Purpose: In this study, it was aimed to investigate the relationship between MS and the homeostatic state of trace elements,and to reveal the relationship between Fe and Zn in MS pathologyMaterial and Method: Total of 40 (20 patients and 20 control) subjects were participated to this study. Blood samples weretaken and analysed plasma iron and zinc levels using an atomic Absorption Spectrophotometer. Kolmogrow-Smirnov Z testused to analyse statistically significance of the data. P<0.05 was accepted as significant.Results: The plasma iron and Zn levels were found to be significantly lower in MS patients compared to control.Conclusion: Considering the important beneficial effects of iron and zinc against neurodegenerative disease and increasedoxidative stress, reduced level of these trace elements should be considered in MS treatment.