Open AccessResistant Chorea Successfully Treated with Intravenous Immunoglobulin: A Case Report
Author(s) -
Ahmet Sami Güven,
Mehmet Burhan Oflaz,
Fatih Bolat,
Utku Aygüneş,
Füsun Dilara İçağasıoğlu
Publication year - 2021
Publication title -
the journal of pediatric academy.
Language(s) - English
Resource type - Journals
ISSN - 2718-0875
DOI - 10.51271/jpea-2021-0146
Subject(s) - chorea , medicine , carbamazepine , therapeutic plasma exchange , valproic acid , chlorpromazine , intravenous immunoglobulins , haloperidol , anesthesia , lamotrigine , antibody , pediatrics , pharmacology , dopamine , immunology , epilepsy , psychiatry , disease
Sydenham’s chorea (SC) is common cause of acquired chorea in childhood. SC occurs mainly in children with untreated streptococcal infections. An effective list of therapeutic options has been used to treat this disorder: antiepileptic drugs (valproic acid, carbamazepine etc.), haloperidol, chlorpromazine, amphetamines, steroids, plasma exchange and intravenous immunoglobulins (IVIG). We report a 12-year-old girl with carditis and severely generalized chorea and successfully treated with IVIG. This case report shows that IVIG is an effective treatment for the chorea cases resistant to anticonvulsants, dopamine antagonists and steroids, although larger studies are needed to confirm this conclusion.