Open AccessINHIBITION OF SURGICALLY INDUCED MIOSIS WITH NEPAFENAC
Author(s) -
Rabbia Mirza,
Imran Basit,
Safdar A. Khan,
Zahid Ullah,
Shahid Tarar,
Muhammad Awais
Publication year - 2021
Publication title -
pakistan armed forces medical journal
Language(s) - English
Resource type - Journals
eISSN - 2411-8842
pISSN - 0030-9648
DOI - 10.51253/pafmj.v71i3.3324
Subject(s) - mydriasis , medicine , miosis , phacoemulsification , cataract surgery , pupil , surgery , ophthalmology , anesthesia , visual acuity , neuroscience , biology
Objective: To assess the efficacy of prophylactic administration of 0.1% nepafenac in the maintenance of trans-operative mydriasis following cataract surgery.
Study Design: Quasi-experimental study.
Place and Duration of Study: Armed Forces Institute of Ophthalmology, Rawalpindi, from Oct 2018 to Mar 2019.
Methodology: A total of 70 patients undergoing cataract surgery phacoemulsification were randomly placed in either the control group or the nepafenac group. Nepafenac eye drops were administered as one drop 8 hourly, 3 days before surgery. Control group didn’t receive any medication preoperatively Mydriasis was measured trans-operatively before surgery, after aspiration of the cortex, and then at the end of surgery. Patients of both groups received tobradex 2 weeks post-surgery.
Results: Post-surgery statistically significant (0.001) difference was observed in the mean pupil size between the nepafenac group (7.88 ± 0.49) and the control group (6.57 ± 0.92 mm).
Conclusion: Use of nepafenac prophylactically was very effective in maintenance of trans-operative mydriasis in cataract surgery.