z-logo
open-access-imgOpen Access
COMPARISON OF SEVOFLURANE VERSUS PROPOFOL FOR TRACHEAL INTUBATION IN CHILDREN
Author(s) -
Zulfiqar Ali,
Azhar R. Hussain,
Aamer Mahmood Malik,
Arslan Saeed Ahmed,
Muhammad Saqib,
Anjum Anwar Qadri
Publication year - 2021
Publication title -
pakistan armed forces medical journal
Language(s) - English
Resource type - Journals
eISSN - 2411-8842
pISSN - 0030-9648
DOI - 10.51253/pafmj.v71i3.3229
Subject(s) - medicine , intubation , anesthesia , sevoflurane , propofol , mean arterial pressure , hemodynamics , tracheal intubation , mean blood pressure , blood pressure , heart rate , surgery
Objective: To compare the quality of intubation and hemodynamic response in children undergoing endotracheal intubation facilitated with propofol versus sevoflurane. Study Design: Quasi-experimental study. Place and Duration of Study: Department of Anesthesia, Combined Military Hospital Multan, from Aug 2018 to Apr 2019. Methodology: A total number of 112 children planned for tracheal intubation were included in this randomized controlled trial. Patients were randomly allocated into two equal groups. In group P (propofol) patient’s 2.5-3.0 mg/kg propofol was given before insertion of endotracheal tube and in group S (sevoflurane) patients 8.0% sevoflurane with 100% O2. Quality of intubation was assessed in all children at the time of intubation. Hemodynamic response of patients was also noted before induction of anesthesia, immediately after intubation and after 5 minutes of intubation. Results: Mean age of children included in this study was 2.11 ± 0.80 years. Quality of intubation was excellent in 51 (91.1%) patients in propofol group and in 38 (67.9%) patients in sevoflurane group (p-value 0.009). Mean HR after 5 minutes of intubation in group S and group P 111.98 ± 5.43 beats/min versus 109.05 ± 5.99 beats/min with p-value 0.008. Mean arterial pressure after 3 minutes of intubation mean arterial pressure in group S and P was 74.58 ± 4.45 mmHg versus 71.0 ± 3.90 mmHg with p-value <0.001. After 5 minutes of intubation mean arterial pressure in group S and P was 73.16 ± 4.13 mmHg versus 68.61 ± 4.07 mmHg with p-value <0.001. Conclusion: Sevoflurane was found to be associated

The content you want is available to Zendy users.

Already have an account? Click here to sign in.
Having issues? You can contact us here