Open AccessCLINICAL PROFILE AND SHORT TERM OUTCOME OF HYPOXIC ISCHEMIC ENCEPHALOPATHY AMONG BIRTH ASPHXIATED BABIES IN A TERTIARY CARE HOSPITAL
Author(s) -
Hafsa Niaz,
Jawad Jalil,
Qamar uz Zaman Khan,
Faisal Basheer,
Shahzad Akhtar,
Naila Hamid
Publication year - 2021
Publication title -
pakistan armed forces medical journal
Language(s) - English
Resource type - Journals
eISSN - 2411-8842
pISSN - 0030-9648
DOI - 10.51253/pafmj.v71i1.3847
Subject(s) - medicine , asphyxia , perinatal asphyxia , encephalopathy , hypoxic ischemic encephalopathy , meconium , gestational age , pediatrics , asphyxia neonatorum , low birth weight , mechanical ventilation , birth weight , neonatal intensive care unit , obstetrics , pregnancy , fetus , anesthesia , biology , genetics
Objective: To determine the clinical profile, selected antepartum and intrapartum risk factor for adverse shortterm outcomes of hypoxic ischemic encephalopathy in babies with birth asphyxia.
Study Design: Cross sectional study.
Place and Duration of Study: Neonatal Intensive Care Unit of Pak Emirates Military Hospital, Rawalpindi, fromJan to Dec 2018.
Methodology: This study including all birth asphyxiated babies born who fulfilled the inclusion criteria.Following data was collected prospectively regarding gender, gestational age, birth weight and mode of delivery, maternal age, antenatal follow up, history of premature rupture of membranes and meconium stained liquor. Babies were categorized into different stages of hypoxic ischemic encephalopathy according to Sarnat and Sarnat staging. Selected antepartum and intrapartum risk factors leading to hypoxic insult at birth were studied and short-term outcome was recorded in the form of need of mechanical ventilation, mortality and discharge from the hospital.Results: The frequency of birth asphyxia turned out to be 122/5986 (2.03%) at our center. Thirty four (27.87%)required mechanical ventilation, mortality was recorded at 20/122 (16.39%). While 61 (50%) babies suffered from stage I hypoxic ischemic encephalopathy, 13/20 (65%) of newborn who expired were suffering from grade III hypoxic ischemic encephalopathy.
Conclusion: The severity of hypoxic ischemic encephalopathy affects the outcome of newborns having birthasphyxia with hypoxic ischemic encephalopathy grade III associated with maximum mortality. Early identifycation of pregnancies at risk for asphyxia, with appropriate intervention in selected cases is the key to prevent birth asphyxia and its ensuing neonatal complications.