Open AccessA comparative study on effect of platelet rich plasma Vs conventional dressing in healing rate of chronic diabetic ulcers
Author(s) -
Swathika Rajendran,
Manuneethimaran Thiyagarajan,
Balaji Singh K.,
Nitesh Navrathan
Publication year - 2021
Publication title -
biomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.498
H-Index - 26
ISSN - 0970-2067
DOI - 10.51248/.v41i4.121
Subject(s) - medicine , granulation tissue , platelet rich plasma , diabetic foot , wound healing , diabetic foot ulcer , diabetes mellitus , surgery , chronic wound , diabetic ulcers , platelet , endocrinology
and Aim: This study has been undertaken to evaluate efficacy of platelet rich plasma (PRP) dressing that is recently introduced with conventional dressing. We have tried to compare PRP dressing with conventional normal dressing in healing the wound. Materials and Methods: We conducted this study in 120 patients of chronic non healing diabetic foot ulcers who were treated over the period of three years. Number of cases (60 each) were studied for efficacy of applying autologous platelet rich plasma versus normal dressing for chronic non healing diabetic foot ulcers. At every week follow up, the ulcer was examined for granulation tissue, area and volume which was calculated using Vernier calipers and marked on a graph paper and photographs were taken. Wound healing was compared between PRP and normal dressing. Results: The incidence of male susceptibility was more (70%) than females (30%) in diabetic foot. Average rate of healing per week was found to be significantly better among the PRP group than normal dressing group. The ulcer showed significant reduction in size among the PRP group in comparison to the normal dressing group with a significant P value (0.001). Conclusion: In this study application of platelet rich plasma into chronic non-healing diabetic foot ulcers in comparison with conventional dressing has shown a significant reduction in the size of the ulcer, hospital stay and cost for the patient.