Open AccessAnti-inflammatory activity of nutmeg oleoresin mediated silver nanoparticles- An In- vitro study
Author(s) -
Shivani Narendra,
Anitha Roy,
Rajeshkumar Shanmugam,
Lakshmi Thangavelu
Publication year - 2020
Publication title -
biomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.498
H-Index - 26
ISSN - 0970-2067
DOI - 10.51248/.v39i2.186
Subject(s) - nutmeg , silver nanoparticle , oleoresin , myristica fragrans , anti inflammatory , chemistry , traditional medicine , pharmacology , pungency , nanoparticle , food science , medicine , materials science , nanotechnology , pepper
and Aim: The most emerging area of research in nanotechnology deals with the synthesis of nanoparticles which are of great importance due to its use in various biological fields. Myristica fragrans is commonly known as “nutmeg”. It is popular as a spice and also possesses various therapeutic properties. It has a characteristic pleasant fragrance and a slightly warm taste. It has various therapeutic uses and is widely used. The aim is to assess the anti-inflammatory activity of nutmeg oleoresin mediated silver nanoparticles.
Materials and Methods: The nutmeg oleoresin mediated silver nanoparticles were synthesized and was confirmed by UV Vis spectroscopy. The anti-inflammatory property of the prepared nutmeg oleoresin mediated silver nanoparticles was assessed using albumin denaturation inhibitory assay technique.
Results: The nutmeg oleoresin mediated silver nanoparticles showed good anti-inflammatory activity with increasing concentration of the nanoparticles.
Conclusion: Although a variety of steroidal and non-steroidal anti-inflammatory drugs have been developed, researchers are focusing on natural substances to develop new anti-inflammatory agents. Nutmeg mediated silver nanoparticles showed a good range of inhibition and can be used against inflammation. The myristicin present in the nutmeg maybe responsible for its anti-inflammatory action. Increased albumin denaturation is reported in conditions like in rheumatoid arthritis, diabetes and cancer. Hence this may pay way to manage such conditions.