Are we still scratching the surface? A case of intractable pruritus following systemic opioid analgesia | Zendy

Dana Tarcatu | Zendy; Cristina Tamasdan | Zendy; Natalie Moryl | Zendy; Eugenie A.M.T. Obbens | Zendy

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Are we still scratching the surface? A case of intractable pruritus following systemic opioid analgesia

Author(s) -

Dana Tarcatu,

Cristina Tamasdan,

Natalie Moryl,

Eugenie A.M.T. Obbens

Publication year - 2007

Publication title -

journal of opioid management

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.331

H-Index - 39

eISSN - 2375-0146

pISSN - 1551-7489

DOI - 10.5055/jom.2007.0055

Subject(s) - hydromorphone , medicine , itching , scratching , oxycodone , opioid , anesthesia , fentanyl , morphine , systemic administration , (+) naloxone , dermatology , physics , receptor , microbiology and biotechnology , in vivo , acoustics , biology

This article describes a case of severe opioid-induced pruritus following systemic morphine administration. Symptoms did not resolve after administration of antihistamines or rotation to fentanyl or hydromorphone, but oral oxycodone and small-dose intravenous naloxone did alleviate the patient’s itching. The pathogenesis of opioidinduced pruritus and the rationale for opioid rotation are briefly discussed. Current and possible future therapeutic options are mentioned.

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