Open AccessColistin-induced Bartter-like Syndrome: Ponder before Treatment!
Author(s) -
Himanshu Verma,
Parikshaa Gupta,
Anju Kumari,
Ajay Kumar,
Preeti Thakur,
Kavish Sharma
Publication year - 2022
Publication title -
indian journal of critical care medicine/indian journal of critical care medicine
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.317
H-Index - 30
eISSN - 1998-359X
pISSN - 0972-5229
DOI - 10.5005/jp-journals-10071-24117
Subject(s) - medicine , colistin , hypokalemia , hypomagnesemia , metabolic alkalosis , bartter syndrome , intensive care medicine , antibiotics , microbiology and biotechnology , materials science , metallurgy , magnesium , biology
Bartter-like syndrome (BLS) is a constellation of biochemical abnormalities which include metabolic alkalosis, hypokalemia, hypocalcemia, hypomagnesemia with normal kidney function. BLS is a very rare syndrome and can be induced by certain diseases, antibiotics, diuretics, and antineoplastic drugs. Colistin is a polymicrobial bactericidal drug and currently re-emerged as the only salvation therapy against multidrug resistant bacilli especially in critically ill patients at intensive care units. Only an anecdotal case report of colistin-induced Bartter-like syndrome has been reported. We here report a case series of four critically ill patients who were on treatment with colistin and presented with serious metabolic disturbances.