Open AccessGene Therapy in Periodontal Tissue Engineering
Publication year - 2007
Publication title -
cods - journal of dentistry
Language(s) - English
Resource type - Journals
ISSN - 2230-8695
DOI - 10.5005/jp-journals-10063-0011
Subject(s) - regeneration (biology) , tissue engineering , genetic enhancement , extracellular matrix , gene delivery , gene , wound healing , biology , microbiology and biotechnology , computational biology , bioinformatics , genetics
An elaborate system of signaling molecules regulates the cellular and molecular events of periodontal healing, the primary strategy for which is functional periodontal compartment regeneration and replication of components of the natural cellular microenvironment by providing an artificial extracellular matrix and by delivering growth factors. A new, so-called gene delivery method works by converting cells into protein- producing factories, thereby bypassing the dilemma. Gene therapy can channel the cellular signals in a controlled and very systematic manner, to provide encoded proteins at every stage of tissue regeneration. The aim of this review is to highlight the applications of gene delivery and tissue engineering in periodontal regeneration. How to cite this article Lakhani N, Vandana KL. Gene Therapy in Periodontal Tissue Engineering. CODS J Dent 2016;8(1):46-48.