Open AccessHereditary Elliptocytosis
Author(s) -
PS Sharmila,
Kannupriya LNU,
MF Paul
Publication year - 2015
Publication title -
the journal of medical sciences/journal of medical sciences
Language(s) - English
Resource type - Journals
eISSN - 2455-6254
pISSN - 2321-354X
DOI - 10.5005/jp-journals-10045-0012
Subject(s) - asymptomatic , pathophysiology , medicine , hemolytic anemia , anemia , pathology , asymptomatic carrier , peripheral blood , immunology
Hereditary elliptocytosis (HE) is a group of disorders characterized by the presence of elliptical-shaped erythrocytes on peripheral blood smear. Hereditary elliptocytosis and its related disorders are characterized by clinical, biochemical, and genetic heterogeneity. Manifestations range from the asymptomatic carrier state to severe, transfusion dependent hemolytic anemia. Abnormalities of various membrane protein defects contribute to mechanical defects of the erythrocyte membrane skeleton. We present a rare case of HE, an incidental finding without any clinical symptoms related to it. We also discuss on pathophysiology and being. How to cite this article Sharmila PS, Kannupriya, Paul MF. Hereditary Elliptocytosis. J Med Sci 2015;1(2):41-43.