Open AccessHelicobacter pylori Infection and Gastric Microbiota
Author(s) -
Gökben Özbey,
E. L. Sproston,
Alfizah Hanafiah
Publication year - 2020
Publication title -
euroasian journal of hepato-gastroenterology
Language(s) - English
Resource type - Journals
eISSN - 2231-5128
pISSN - 2231-5047
DOI - 10.5005/jp-journals-10018-1310
Subject(s) - fusobacteria , helicobacter pylori , firmicutes , stomach , biology , proteobacteria , bacteroidetes , microbiology and biotechnology , actinobacteria , gastritis , gut flora , helicobacter , disease , gastroenterology , bacteria , medicine , immunology , 16s ribosomal rna , genetics
Owing to its strong acid production, the stomach was known to be a bacteria-free organ for many years. On the other hand, the presence of Helicobacter pylori ( H. pylori ) and other acid-resistant microbiota that are to persist in the stomach challenged this. It is now recognized that the existence of H. pylori and non- H. pylori species have been linked to the improvement of gastric disease; despite this, there is little published data on the interaction of gastric bacterial flora and the resultant effect on gastric health. The stomach has a unique microbiota including five major phyla, such as Firmicutes, Proteobacteria, Actinobacteria, Fusobacteria and Bacteroidetes. These phyla are identified in both H. pylori -infected and uninfected persons. The resident gastric microflora may mediate the role of H. pylori in the gastric diseases. This article aims to review previous studies that examine the impact of H. pylori infection and the effect of resident gastric microbiota on gut health and disease conditions.