Open AccessMedical Management of Uterine Leiomyoma: A Comprehensive Review
Author(s) -
S Shantha Kumari,
Kiranmai Devineni
Publication year - 2015
Publication title -
journal of south asian federation of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.108
H-Index - 8
eISSN - 0975-1920
pISSN - 0974-8938
DOI - 10.5005/jp-journals-10006-1327
Subject(s) - medicine , uterine artery embolization , leiomyoma , uterine leiomyoma , hysterectomy , uterus , amenorrhea , gynecology , obstetrics , pregnancy , radiology , genetics , biology
Uterine leiomyomas are most common benign tumors that occur in women of reproductive age. They are frequently associated with symptoms that impact on quality of life and require treatment. Treatment was usually surgical with either hysterectomy or myomectomy being performed. Although myomectomy conserves the uterus, it is associated with complications that might not enhance the chance of pregnancy and for those concerned about fertility, alternatives are being developed. Apart from therapeutic modalities like uterine artery embolization, other exciting developments are high intensity focused ultrasound and MRI guided focused ultrasound. New medical treatments are being evaluated—among which the progesterone receptor modulators that induce amenorrhea and a degree of fibroid shrinkage whilst having minimal effect on ovarian function are promising. This article gives a comprehensive overview of medical management of leiomyoma, reviews the literature and suggests further reading. How to cite this article Kumari SS, Devineni K. Medical Management of Uterine Leiomyoma: A Comprehensive Review. J South Asian Feder Obst Gynae 2015;7(2):71-76.