Open AccessThe Association of a Rare Variant of -93, -53 Promoter Gene Polymorphisms of Lipoprotein Lipase Gene with Obesity and Insulin Resistance
Author(s) -
Jai Prakash,
Balraj Mittal,
Ajay Srivastava,
Sanjay Awasthi,
Neena Srivastava
Publication year - 2018
Publication title -
oman medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.395
H-Index - 31
eISSN - 2070-5204
pISSN - 1999-768X
DOI - 10.5001/omj.2018.74
Subject(s) - lipoprotein lipase , insulin resistance , genotyping , promoter , obesity , medicine , genotype , genetics , gene , body mass index , endocrinology , biology , adipose tissue , gene expression
Obesity increases the risk of numerous chronic diseases. Obesity is classified clinically using body mass index (BMI), waist-to-hip ratio, and body fat percentage. The lipoprotein lipase ( LPL ) gene has been linked to lipoprotein metabolism and obesity. We performed a case-control study to determine the association between LPL gene polymorphisms and obesity-associated phenotypes such as insulin resistance (IR).