Evaluation of the Role of -137G/C Single Nucleotide Polymorphism (rs187238) and Gene Expression Levels of the IL-18 in Patients with Coronary Artery Disease | Zendy

Fatemeh Hoseini | Zendy; Sanaz Mahmazi | Zendy; Khalil Mahmoodi | Zendy; Gholam Ali Jafari | Zendy; Mohammad Soleiman Soltanpour | Zendy

Open Access

Evaluation of the Role of -137G/C Single Nucleotide Polymorphism (rs187238) and Gene Expression Levels of the IL-18 in Patients with Coronary Artery Disease

Author(s) -

Fatemeh Hoseini,

Sanaz Mahmazi,

Khalil Mahmoodi,

Gholam Ali Jafari,

Mohammad Soleiman Soltanpour

Publication year - 2018

Publication title -

oman medical journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.395

H-Index - 31

eISSN - 2070-5204

pISSN - 1999-768X

DOI - 10.5001/omj.2018.23

Subject(s) - coronary artery disease , medicine , genotype , odds ratio , allele , single nucleotide polymorphism , gastroenterology , proinflammatory cytokine , gene , immunology , genetics , biology , inflammation

Interleukin-18 (IL-18) is a proinflammatory and proatherogenic cytokine, and its genetic variations may contribute to the development of coronary artery disease (CAD). We sought to investigate the role of -137G/C polymorphism and gene expression levels of IL-18 in patients with CAD.

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