Open AccessAssociation of FTO rs9939609 SNP with Obesity and Obesity- Associated Phenotypes in a North Indian Population
Author(s) -
Jai Prakash,
Balraj Mittal,
Ajay Srivastava,
Sanjay Awasthi,
Neena Srivastava
Publication year - 2016
Publication title -
oman medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.395
H-Index - 31
eISSN - 2070-5204
pISSN - 1999-768X
DOI - 10.5001/omj.2016.20
Subject(s) - obesity , medicine , body mass index , fto gene , endocrinology , single nucleotide polymorphism , population , snp , blood pressure , genotype , genetics , biology , gene , environmental health
Obesity is a common disorder that has a significant impact on morbidity and mortality. Twin and adoption studies support the genetic influence on variation of obesity, and the estimates of the heritability of body mass index (BMI) is significantly high (30 to 70%). Variants in the fat mass and obesity-associated (FTO) gene have been associated with obesity and obesity-related phenotypes in different populations. The aim of this study was to examine the association of FTO rs9939609 with obesity and related phenotypes in North Indian subjects. .