The Effect of Vitamin B12 Infusion on Prevention of Nitrous Oxide-induced Homocysteine Increase: A Double-blind Randomized Controlled Trial | Zendy

Alieh Zamani Kiasari | Zendy; Abolfazl Firouzian | Zendy; Afshin Gholipour Baradari | Zendy; Hamid Sharif Nia | Zendy; Seyed Hosein Moosavi Kiasari | Zendy

Open Access

The Effect of Vitamin B12 Infusion on Prevention of Nitrous Oxide-induced Homocysteine Increase: A Double-blind Randomized Controlled Trial

Author(s) -

Alieh Zamani Kiasari,

Abolfazl Firouzian,

Afshin Gholipour Baradari,

Hamid Sharif Nia,

Seyed Hosein Moosavi Kiasari

Publication year - 2014

Publication title -

oman medical journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.395

H-Index - 31

eISSN - 2070-5204

pISSN - 1999-768X

DOI - 10.5001/omj.2014.48

Subject(s) - medicine , anesthesia , nitrous oxide , placebo , vitamin b12 , homocysteine , hyperhomocysteinemia , anesthetic , saline , randomized controlled trial , inhalation , surgery , alternative medicine , pathology

Nitrous oxide is a common inhalation anesthetic agent in general anesthesia. While it is widely accepted as a safe anesthetic agent, evidence suggests exposure to this gas, leads to hyperhomocysteinemia. The present study aimed to evaluate the effects of single-dose intravenous infusions of vitamin B12, before and after the induction of nitrous oxide anesthesia on homocysteine levels after the surgery.

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