Open AccessThe Effect of Vitamin B12 Infusion on Prevention of Nitrous Oxide-induced Homocysteine Increase: A Double-blind Randomized Controlled Trial
Author(s) -
Alieh Zamani Kiasari,
Abolfazl Firouzian,
Afshin Gholipour Baradari,
Hamid Sharif Nia,
Seyed Hosein Moosavi Kiasari
Publication year - 2014
Publication title -
oman medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.395
H-Index - 31
eISSN - 2070-5204
pISSN - 1999-768X
DOI - 10.5001/omj.2014.48
Subject(s) - medicine , anesthesia , nitrous oxide , placebo , vitamin b12 , homocysteine , hyperhomocysteinemia , anesthetic , saline , randomized controlled trial , inhalation , surgery , alternative medicine , pathology
Nitrous oxide is a common inhalation anesthetic agent in general anesthesia. While it is widely accepted as a safe anesthetic agent, evidence suggests exposure to this gas, leads to hyperhomocysteinemia. The present study aimed to evaluate the effects of single-dose intravenous infusions of vitamin B12, before and after the induction of nitrous oxide anesthesia on homocysteine levels after the surgery.