Open AccessFulminant Streptococcal Toxic Shock Syndrome
Author(s) -
Zavala Sofia,
Manuel Arias,
Pedro Légua
Publication year - 2018
Publication title -
journal of the royal college of physicians of edinburgh/the journal of the royal college of physicians of edinburgh
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.275
H-Index - 26
eISSN - 2042-8189
pISSN - 1478-2715
DOI - 10.4997/jrcpe.2018.107
Subject(s) - medicine , fulminant , rash , toxic shock syndrome , respiratory distress , vomiting , shock (circulatory) , disseminated intravascular coagulation , nausea , tachycardia , coagulopathy , septic shock , pancytopenia , anesthesia , respiratory failure , streptococcus pyogenes , surgery , sepsis , bone marrow , biology , bacteria , genetics , staphylococcus aureus
We present a case of a previously healthy 37-year-old male who developed fever, nausea, vomiting, diarrhoea, and hypovolaemia. Within 5.5 h he presented with tachycardia, tachypnoea, became hypotensive and displayed a diffuse erythematous rash. In the following hours he developed persistent hypotension, acute respiratory distress syndrome, liver failure, kidney failure and disseminated intravascular coagulation. A diagnosis of toxic shock syndrome was made, but despite antibiotic therapy, immunoglobulin administration, and supportive measures, the patient died 50 h after presentation. Streptococcus pyogenes was isolated from blood cultures.