Open AccessThe mechanism of mammalian mitochondrial quality control system
Author(s) -
Safir Ullah Khan,
Munir Ullah Khan
Publication year - 2021
Publication title -
journal of chemistry and nutritional biochemistry
Language(s) - English
Resource type - Journals
ISSN - 2709-5932
DOI - 10.48185/jcnb.v2i2.387
Subject(s) - mitochondrion , microbiology and biotechnology , reactive oxygen species , mechanism (biology) , cell metabolism , biology , function (biology) , energy metabolism , cell function , cell , biochemistry , philosophy , epistemology , endocrinology
The mitochondria perform an essential role in cellular metabolism by acting as a cellular energy powerhouse. It is also involved in several biological processes such as cell metabolism, stress signaling, calcium homeostasis, and reactive oxygen species(ROS) and apoptosis. Maintaining cellular physiological function is strongly dependent on mitochondrial quality control. mitochondrial malfunction will lead to various disorders. For this review, we evaluate the current understanding of the molecular mechanism of mitochondria quality control, which might also serve as an asset for organisms' health and the prevention of disease