Open AccessSynthesis and Structural Characterization of 16-Membered Schiff Base Macrocycles
Author(s) -
S. N. Ibatte
Publication year - 2022
Publication title -
international journal of advanced research in science, communication and technology
Language(s) - English
Resource type - Journals
ISSN - 2581-9429
DOI - 10.48175/ijarsct-2617
Subject(s) - bacillus subtilis , ethylenediamine , schiff base , chemistry , antibacterial activity , nuclear chemistry , escherichia coli , metal , perchloric acid , divalent , inorganic chemistry , polymer chemistry , organic chemistry , bacteria , biochemistry , biology , genetics , gene
Novel tetraazamacrocyclic complexes of Cu(II), Co(II), Ni(II) and Zn(II) has been synthesized from the reaction of ethylenediamine with Meldrums acid and divalent metal ions using solid-supported perchloric acid (HClO4-SiO2) as a catalyst. The complexes were characterized by IR, 1HNMR, EPR spectra, magnetic moments, conductance, thermal analysis (TGA and DTA), and powder X-ray analysis (XRD). The antimicrobial studies of these complexes against Staphylococcus typhi, Staphylococcus aurieus, Escherichia coli, Bacillus subtilis species by Minimum Inhibitory Concentration (MIC) method revealed that these complexes possess potent antibacterial activity.