Open AccessPreparation and Evaluation of Herbal Anti-Inflammatory Gel
Author(s) -
Shrikant M. Madhekar,
Amanpreetkaur Dumda,
Pinjari Juned Shaikh Ismail,
Baig Ubaid Quader Baig
Publication year - 2021
Publication title -
international journal of advanced research in science, communication and technology
Language(s) - English
Resource type - Journals
ISSN - 2581-9429
DOI - 10.48175/ijarsct-2072
Subject(s) - medicine , traditional medicine , xanthan gum , skin irritation , irritation , population , dermatology , rheology , environmental health , materials science , immunology , composite material
Herbal medicines is still the mainstay of about 75-80% of the world’s population, mainly in developing countries, for primary health care because of better cultural acceptability, better compatibility with human body and lesser side effects. Herbal medicines consist of plant or its part to treat injuries, disease or illnesses and are used to prevent and treat diseases and ailments or to promote health and healing. It is a drug or preparation made from a plant or plants and used for any to such purpose. Herbal medicines are the oldest form of health care known to mankind. Gel formulations prepared with Carbopol 934, HPMC K 100 M and Xanthan gum showed good homogeneity, no skin irritation, good stability and anti-inflammatory activity. However, the Xanthan gum based gel proved to the formula of choice, since it showed the highest percentage of extrudability, good spreadability and rheological properties. Formulation F1 and F5 showed the best formulation with significant anti-inflammatory activity. Formulation 1 and F5 shows approximately equal anti-inflammatory activity.