Open AccessSolid Lipid Nanoparticles: A Brief Review
Author(s) -
Amol Giri,
Aijaz Sheikh,
P R Tathe,
G R Sitaphale,
K. R. Biyani
Publication year - 2021
Publication title -
international journal of advanced research in science, communication and technology
Language(s) - English
Resource type - Journals
ISSN - 2581-9429
DOI - 10.48175/ijarsct-1759
Subject(s) - solid lipid nanoparticle , bioavailability , nanotechnology , drug delivery , nanoparticle , pulmonary surfactant , drug , chemistry , materials science , pharmacology , medicine , biochemistry
In this present review this new approach of solid lipid Nanoparticles (SLNs) is discussed in terms of their aims, advantages, and disadvantages, methods of preparation, characterization and special features. In the state of developments in the research and development of new drug delivery systems have been made in Last decade by resolving various disorders, such as Low Drug Bioavailability and unpredictable gastric emptying era. Most of the active pharmaceutical ingredients are under poor bioavailability and also their solubility. By using the nanotechnology to overcome this problems of novel drug delivery system. The main advantage of nanotechnology i.e. solid lipid Nanoparticles increases the bioavailability and elimination biological half-life of the drugs. Solid lipid Nanoparticles are spherical lipid particles ranging in size from 1 to 1000 nm and are dispersed in water or in aqueous surfactant solution.