Open AccessGenetic and epigenetic bases of prostate tumor cell radioresistance
Author(s) -
Денис С. Кутилин
Publication year - 2021
Publication title -
klinická onkologie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.204
H-Index - 13
eISSN - 1802-5307
pISSN - 0862-495X
DOI - 10.48095/ccko2021220
Subject(s) - radioresistance , cancer research , epigenetics , microrna , prostate cancer , biology , copy number variation , cancer , gene , genetics , cell culture , genome
Radiation therapy plays a leading role in the treatment of prostate cancer, but the emergence of radioresistant forms of this disease dictates the need for a personalized ap-proach based on the data from genetic and epigenetic markers. Such markers include the copy number variation as well as gene and microRNA expression.