Open AccessPharmacodynamic drug interactions
Author(s) -
Hocine Gacem,
Département de Pharmacie. Faculté de Médecine de Batna – Algérie.,
Amel Ahmane
Publication year - 2014
Publication title -
batna journal of medical sciences
Language(s) - English
Resource type - Journals
ISSN - 2437-0665
DOI - 10.48087/bjmstf.2014.1210
Subject(s) - pharmacodynamics , drug action , drug , action (physics) , pharmacology , drug drug interaction , antagonism , medicine , computational biology , biology , pharmacokinetics , receptor , physics , quantum mechanics
Pharmacodynamic interactions are manifested by a change in pharmacological effect at the site of action. There may be a synergistic action, a potentiation or antagonism. Pharmacodynamic interactions are predictable and preventable since the mechanisms of drug action are defined in advance, the interaction drug-target is systematically described and various effectors and signal transduction systems are highlighted. Any time the plurality of molecular targets of the same drug should be considered when prescribing. The wide diffusion of pharmacological information and the updating of knowledge are then two tools to manage this kind of interaction.