Open AccessSynergism of Zinc Oxide Nano-Powder with Active Compound from Turmeric and Lemongrass as Bacterial Inhibitor
Author(s) -
Gee Een Lau,
Che Azurahanim Che Abdullah,
Mohd Sabri Mohd Ghazali,
Muhamad Syazlie Che Ibrahim
Publication year - 2021
Publication title -
walailak journal of science and technology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.146
H-Index - 15
eISSN - 2228-835X
pISSN - 1686-3933
DOI - 10.48048/wjst.2021.9652
Subject(s) - antibacterial activity , agar diffusion test , zinc , nuclear chemistry , chemistry , staphylococcus aureus , antimicrobial , bacteria , nanoparticle , escherichia coli , pathogenic bacteria , food science , materials science , nanotechnology , biochemistry , organic chemistry , biology , genetics , gene
Green nanoparticles are receiving great attention due to their broad fields of application. Plant extracts are promising sources, since the synergizing process is easy and cost-effective. Green synergism offers safer nanomaterials for both human health and the environment. The antimicrobial application of prepared nanoparticles is due to special capabilities at the nanoscale size. Green zinc oxide nanoparticles (ZnONPs) from lemongrass and turmeric revealed good antibacterial properties. Antibacterial active compounds were extracted from lemongrass and turmeric using methanol as a solvent. The extracts were introduced to zinc oxide solution to create synergized green ZnONPs and tested for their antibacterial properties. The samples were characterized by means of XRD, SEM, FTIR, and GC-MS. The zones of inhibition of synergized green ZnONPs were successfully measured using the disc diffusion method. The findings using gram-negative bacteria Escherichia coli. showed a higher antibacterial inhibition zone, with a diameter of 1.6 cm. The gram-positive bacteria, Staphylococcus aureus., showed low antibacterial inhibition. The addition of ZnO had positively revealed greater inhibition. Green ZnONPs synthesized using plant extracts will be further tested for various applications.HIGHLIGHTSGreen zinc oxide nanoparticles (ZnONPs) prepared from lemongrass and turmericsPlant extracts are significant in reducing and stabilizing metallic ionsThe synergism of ZnONPs was successfully prepared from plant extract active and evaluated for their antibacterial activity using Staphylococcus aureus and Escherichia coliThe zones of inhibition of synergized green ZnONPs measured using the disc diffusion method showed a higher antibacterial inhibition zoneAntibacterial activity revealed the potential applications of green synergism of ZnONPs for treatment of contaminated water, medical applications, and cosmeticsGRAPHICAL ABSTRACT