Open AccessFactors Influencing Early Neurological Recovery in Patients with Acute Ischemic Stroke
Author(s) -
Orapen Sukhavulli,
Siriorn Sindhu,
Wanpen Pinyopassakul,
Chukiat Viwatwongkasem
Publication year - 2018
Publication title -
walailak journal of science and technology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.146
H-Index - 15
eISSN - 2228-835X
pISSN - 1686-3933
DOI - 10.48048/wjst.2019.4063
Subject(s) - medicine , stroke (engine) , logistic regression , ischemic stroke , anesthesia , gastroenterology , ischemia , mechanical engineering , engineering
The purposes of this cross-sectional descriptive study were to describe early neurological recovery in patients with acute ischemic stroke and to identify the statistical predictors of early neurological recovery at 24 h and 3 days after admission. A purposive random sampling was employed to recruit 220 AIS patients from 8 hospitals in the southern region of Thailand from January to May 2016, and the data was analyzed by using multivariate logistic regression analysis. The results revealed that moderate and severe stroke severity decreased neurological recovery at 24 h (OR = .095, p 80 years decreased neurological recovery at 24 h after admission (OR=.361, P < .05). Neurological recovery at 3 days showed that moderate and severe stroke severity decreased neurological recovery (OR = .10, p < .001, and OR = .09, p < .001, respectively), compared with mild stroke severity. Stroke patients who had onset time to rt-PA within 3 h and within 3.0 - 4.5 h increased neurological recovery at 3 days (OR=16.95, P < .05, and OR = 14.43, P < .01, respectively), compared with those who did not receive rt-PA treatment. The findings of this study show that stroke severity and onset time to rt-PA influence early neurological recovery in AIS patients.