The Effects of Resistance Exercise in End Stage Renal Disease Patients Undergoing Hemodialysis: A Systematic Meta-Analysis

End-stage renal disease (ESRD) is a global public health problem as same as in Thailand the number of patients undergoing hemodialysis treatment is getting higher every year. In frequently cases has many impacts and affect the reduction of functional conditions. The objective of this study is to conduct a systematic review and meta-analysis of research into the effects of resistance exercise on end stage renal disease patients undergoing hemodialysis and to analyze the effect size of resistance exercise on patients. A systematic literature search was conducted using the database of Science direct, Wiley Online Library, Scopus, PubMed, EBSSCO host and the Thai-Journal Citation Index Center, looking for randomized controlled trials between 2009 and 2020. Combined effect sizes were calculated using Review Manager Version 5.3. Eight articles met the inclusion criteria and in the effect size analysis.  Results showed that resistance exercise improved the ability to function and increased muscle strength, improved body composition and quality of life in chronic renal failure patients undergoing hemodialysis treatment. HIGHLIGHTS The effectiveness of resistance exercise interventions improves physical performance, quality of life (QOL), muscle strength and body composition The characteristic of exercise has shown to be high beneficial for many health aspects and easily modifiable lifestyle factor with virtually no negative side effects  This meta-analysis might help to develop early intervention strategies for physical and psychological outcome both of patients with chronic diseases GRAPHICAL ABSTRACT