Open AccessSpeckled Pigmentation and Palmoplantar Keratoses Leading to the Mass Detection of Chronic Arsenic Poisoning
Author(s) -
Sheena Maureen T. Sy,
Charissa Salud-Gnilo,
Ella Joy Nogas-Perez
Publication year - 2017
Publication title -
acta medica philippina/acta medica philippina
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.128
H-Index - 4
eISSN - 2094-9278
pISSN - 0001-6071
DOI - 10.47895/amp.v51i2.619
Subject(s) - dermatology , medicine , dyskeratosis , hyperkeratosis , keratolytic , arsenic , arsenic poisoning , chemistry , organic chemistry
Arsenic is a known human carcinogen and skin manifestations are the earliest and most specific markers of chronic arsenic poisoning. A 43-year-old man from Luzon presented at the Section of Dermatology with a one-year history of hyperkeratotic papules and plaques on the palms and soles. Numerous round hypopigmented macules were scattered on the upper back. Initial 24-hour urine arsenic level was elevated at 288mcg/liter. The patient underwent successful chelation with Nacetylpenicillamine and the palmoplantar keratoses were treated with cryotherapy and topical 20% salicylic acid in white petrolatum. In cooperation with the Department of Health, a comprehensive health and environmental assessment was conducted in the affected communities. This case highlights the role of dermatologists in the diagnosis and management of this public health problem.