Open AccessAssessment of tolerance and acceptability between mannitol solution and polyethylene glycol as bowel preparation for colonoscopy: a three-center study
Author(s) -
Jean Félix Piñ Erúa-Gonsá Lvez,
Rosanna Del Carmen Zambrano-Infantino,
Alberto Baptista,
Mariseli Sulbaran,
Noheltriz Camaray
Publication year - 2020
Publication title -
revista de gastroenterología del perú
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.148
H-Index - 15
eISSN - 1609-722X
pISSN - 1022-5129
DOI - 10.47892/rgp.2020.401.1023
Subject(s) - bloating , medicine , colonoscopy , bowel preparation , mannitol , peg ratio , polyethylene glycol , enema , laxative , abdominal pain , gastroenterology , colorectal cancer , constipation , cancer , chemistry , organic chemistry , finance , economics
Adequate bowel preparation is one of the most important factors related to the yield of colonoscopy. Low-quality bowel preparation has been associated with lower adenoma detection rates and increased healthcare expenses. Bowel preparation is a major impediment to undergo colonoscopy since it is perceived as an unpleasant experience by patients. Objective: This study was aimed to assess tolerance and acceptability of the bowel preparation using either polyethylene glycol (PEG) or mannitol solution. Materials and methods: We enrolled 140 patients with indications of screening for colorectal cancer or with suspected large bowel diseases. They received either mannitol solution or PEG as bowel preparation. Patients were asked to fill a questionnaire about the bowel preparation experience. Results: Patients perceived more burdensome the preparation with PEG than mannitol for the variables nausea overall experience, post-procedure discomfort, disagreeable flavor, volume ingested and cost (p 0.05). The acceptability was 82.9% and 71.4% in the Mannitol group and in the PEG group, respectively (p=0.10). Conclusion: Acceptance of the bowel preparation between mannitol solution and PEG was comparable. However, mannitol was bettertolerated by the patients in regard to most of the evaluated items.