Open AccessAssessment of the rate of human aging by clinical biochemical tests
Author(s) -
Anatoly Pisaruk,
Ivanna Antoniuk-Shcheglov,
Світлана Наскалова,
Olena Bondarenko,
Valerii Shatylo,
Ludmila Mekhova
Publication year - 2021
Publication title -
ageing and longevity
Language(s) - English
Resource type - Journals
ISSN - 2709-0205
DOI - 10.47855/jal9020-2021-1-4
Subject(s) - anthropometry , stepwise regression , regression analysis , regression , physiology , statistics , medicine , gerontology , biology , mathematics
The aim of the study was the development of the accessible method for assessing the rate of human aging by laboratory biochemical parameters. There were examined 408 practically healthy people in the age from 20 to 80 years. There were determined 6 anthropometric and 14 laboratory biochemical parameters, characterizing carbohydrate and fat metabolism, liver and kidney functions.The use of stepwise multiple regression made it possible to select the most informative indicators and obtain an equation linking the age of the examined people with a number of anthropometric and metabolic indicators. The average absolute error in calculating age was 4.2 years.The method for assessing the rate of aging, developed by us, is highly accurate and can be used to assess the risk of developing of the age-dependent pathology.