Open AccessVitamin D and COVID-19: Insight on Mechanism and Implementation in Equatorial Countries
Author(s) -
Indah Bachti Setyarini,
Nurul Ratna,
Ninik Mudjihartini
Publication year - 2021
Publication title -
journal of the indonesian medical association
Language(s) - English
Resource type - Journals
eISSN - 2654-3796
pISSN - 2089-1067
DOI - 10.47830/jinma-vol.71.2-2021-354
Subject(s) - immune system , vitamin d and neurology , covid-19 , pandemic , mechanism (biology) , coronavirus , equator , vitamin , disease , population , medicine , immunology , intensive care medicine , biology , environmental health , infectious disease (medical specialty) , geography , physics , geodesy , latitude , quantum mechanics
Coronavirus disease 2019 (COVID-19) is a global pandemic caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection, affecting millions of people worldwide due to its ease of transmission. Despite limited information on effective therapeutic options, vitamin D has been regularly reported to exert beneficial immunomodulatory effects affecting both innate and adaptive immune systems. As it is synthesized in the skin under ultraviolet radiation, population living in equatorial countries are presumed to have adequate vitamin D, however several studies have shown otherwise. This article is aimed to give an insight on the different mechanisms by which vitamin D affects our immune system in COVID-19, as well as discussing correlation of having sunlight all year round by being near the equator towards vitamin D adequacy.