A Comparative Study of Pulmonary Functions in Patients with Type 2 Diabetes Mellitus and Normal Individuals

Background: Diabetes mellitus is a multi-system disorder thataffects many organs of the bodyincluding the lung. Thus, thelung is considered a 'target organ' in diabetes mellitus.Thepresent study is undertaken to evaluate the impact of type2 diabetes mellitus onpulmonary functions of adult malediabetic patients and to compare between type 2diabetesmellitus patients and healthy adult male subjects.Methods: Hundred adult male type 2 diabetic patients wereselected from the diabetic clinic,Prathima Institute of Medical Sciences, Nagunur, Karimnagar,and 100 adult male healthy subjects were selected randomlyamong the general population from Karimnagar city.spirograms were recorded by Spirowin PC-basedSpirometer.Parameters such as Forced Vital Capacity (FVC), ForcedExpiratoryVolume in 1st second (FEV1), the ratio of FEV1/FVC,Forced Expiratory Flow (FEF) inthe Middle Half of FVC, andPeak Expiratory Rate (PEFR) were assessed and analyzedbyusing the paired t-test and ANOVA.Results: Diabetes mellitus has a negative impact on pulmonaryfunctions when compared with healthy subjects. In this studytype 2 diabetes mellitus patients showed a significantly greaterpercentage decline in FVC, FEV1, FEF25-75%, PEFR, and a slightincrease in the ratio of FEV1/FVC suggestive of the restrictivepulmonary disorder.Conclusion:This study found the pulmonary functions FVC, FEV1,FEF25%-75%, and PEFR are decreased inType 2 diabetesmellitus compared to controls. FEV1/FVC% slightly increasedin Type 2 diabetes mellitus, which is indicative of the restrictivepulmonary disorder