Clinic epidemiological evaluation of co morbidities in patients with psoriasis in a tertiary care hospital

Background: Psoriasis is a common disease presented to thedermatology clinics. There are several reports concerning comorbidities in patients with psoriasis. Some of them includediabetes mellitus, hypertension, dyslipidemia, obesity, IHD,ulcerative colitis. Hence, we in the present study tried toevaluate the existing comorbidities in patients diagnosed withpsoriasis in presenting to our hospital.Methods: This study was conducted in the Department ofDermatology, Venereology, and Leprosy, Prathima Institute ofMedical Sciences, Karimnagar. This case-control studyevaluated the prevalence of diabetes mellitus, hypertension,obesity, dyslipidemia and metabolic syndrome in patients withpsoriasis. The existence of hypertension, diabetes mellitus,dyslipidemia, obesity was determined by standard criteria. Thedata was recorded and analyzed using SPSS version 17 for pvalues.Results: BSL (Blood Sugar Level) derangement as increasedfasting BSL was observed in 23 (23%) cases compared to 8(8%)controls. There was a statistically significant difference betweenpsoriatic cases and controls. The total number of male patientswith raised waist circumference was 24 (33.8%) compared to9(13.2%) controls. There was a statistically significantassociation of raised waist circumference in psoriasis casescompared to controls, the p-value was <0.004. The existenceof metabolic syndrome was 27% in the study group and 8% inthe control group the p values were <0.004 and significant.Conclusion: The results of the present shows that there is asignificant prevalence of psoriasis in males as compared tofemales. There is a significant association of metabolicsyndrome in patients with psoriasis. Hence all the patients withpsoriasis need to be evaluated for metabolic syndrome whichmay be a risk factor for systemic diseases.