
Seasonal trends and laboratory markers of Diabetic Ketoacidosis in type 1 Diabetes: A descriptive study from Maharashtra
Author(s) -
Vijay Gaikwad,
Jeevanand Deshmukh,
Prachi Deshmukh,
Anant A. Takalkar
Publication year - 2020
Publication title -
perspectives in medical research
Language(s) - English
Resource type - Journals
eISSN - 2348-229X
pISSN - 2348-1447
DOI - 10.47799/pimr.0801.05
Subject(s) - hypokalemia , ketonuria , medicine , diabetic ketoacidosis , diabetes mellitus , incidence (geometry) , hyponatremia , pediatrics , type 1 diabetes , ketoacidosis , endocrinology , physics , optics
Defined by the triad hyperglycemia, acidosis, andketonuria, DKA can be inaugural or complicate known diabetes.With many improvements in the treatment of DKA and inunderstanding of the metabolic and electrolyte changes andtheir treatment, it is possible to prevent and treat thiscondition.Objectives: To assess the seasonal trends laboratory profile ofpatients presenting as Diabetic Ketoacidosis (DKA).Methodology: It is a descriptive observational study wasconducted at Department of Medicine, Dr. Shankarrao ChavanMedical College and Hospital, Nanded. The study included 77patients of diabetic ketoacidosis (DKA) from Male Medicineward, Female Medicine ward, Medical Intensive Care Unit. Thestudy was carried out during Jan 2012 to October 2013. Thedata was analyzed using SPSS 24.0 version.Results: 40.3% patients were from 10-20 years age group.Overall incidence of DKA was 0.33% and slightly more in males(0.35%) than in females (0.30%). Cases were more in summerand spring especially high summer i.e. 18.66%. Maximumpatients i.e. 47% have blood sugar level above 600 mg/dl.38(49%) patients showed sodium level slightly lower thannormal. Hypokalemia was observed in 13(17%) patients.Conclusion: Cases were more in summer and spring especiallyduring high summer i.e. 18.66%. BSL was above 600 mg/dl inalmost half of the DKA patients. Hyponatremia andhypokalemia were predominant findings in our study.