Open AccessNANOSPONGES: AN EVOLUTIONARY TREND FOR TARGETED DRUG DELIVERY
Author(s) -
Jawad Bilal,
Sudhanshu Abhishek,
S Bhosale Ankush,
D Raut Indrayani,
M Nitalikar Manojkumar
Publication year - 2021
Publication title -
international journal of pharmaceutical sciences and medicine
Language(s) - English
Resource type - Journals
ISSN - 2519-9889
DOI - 10.47760/ijpsm.2021.v06i06.001
Subject(s) - drug delivery , bioavailability , nanotechnology , nanomedicine , drug , chemistry , delivery system , controlled release , applications of nanotechnology , pharmacology , medicine , materials science , nanoparticle
Recent developments in nanotechnology have made the framework for the growth of new nanoscale biomaterials with numerous potential uses in nanomedicine. The nanosponge is a new and emerging technology that can be used to target medicine delivery in a precise and regulated manner. Nanosponge is an important component of advanced medication delivery. It is a specialized assisting system for regulated medication delivery of both lipophilic and hydrophilic medicines in a regulated manner. Effective medication delivery at a specific location allowed for more exact control of release rates and boosted health-care system compliance, but the chemistry having complex shape complicated things. The invention of nanosponges, on the other hand, has provided significant approach to tackling this problem. The technology of Nanosponge has been studied widely for the delivery of drugs for oral, topical, and parental administration. Enzymes, proteins, vaccines, and antibodies can all be delivered effectively using nanosponges. It is more effective for targeted drug delivery systems because it improves solubility, bioavailability, and decreases side effects by releasing the drug at specific site. It has the ability to improve drug solubility and can be manufactured into oral, topical, and parenteral dose forms. This type of carrier system is best for drugs with low bioavailability. Nanosponges can contain both lipophilic and hydrophilic medicines. Nanosponges are extremely permeable, with a high proclivity for ensuring dynamic particles and programmable delivery. This review article discusses nanosponges in general, their advantages & disadvantages, mechanism; factors influence nanosponge, preparation methods, evaluation parameters as well as applications.