Insulin Delivery Utilizing Hybrid-Closed-Loop Therapy is More Effective When a Single Basal Rate Rather Than Multiple Basal Rates is Utilized - A Case Report

With Continuous Subcutaneous Insulin Infusion (CSII) multiple basal rates need to be utilized to avoid nocturnal hypoglycemia, the dawn phenomenon, postprandial hyperglycemia and preprandial hypoglycemia. With the availability of the Hybrid Closed-Loop Therapy (HCLT) systems, the use of multiple basal rates has become unnecessary and counterproductive. When transferring to a HCLT system we utilize a single basal rate for twenty-four hours. By utilizing a single basal rate we have improved multiple metrics of glycemic control in many patients. To illustrate the benefits of transfer to a single basal rate in a HCLT system we present a relevant case.