To compare the efficacy of timolol maleate 0.5% vs fixed combination of timolol maleate 0.5%, and brimonidine tartrate 0.2% in control of raised intra ocular pressure in patients undergone Nd-Yag laser capsulotomy.

Purpose: The purpose of the study is to compare the efficacy of Timolol maleate alone vs fixed combination of Timolol maleate 0.5% with Brimonidine 0.2% in patients undergone Nd-Yag laser capsulotomy. Methodology:  100 patients with posterior capsular opacification were enrolled though OPD. They were placed in 2 groups with 50 patients each.  Group A received Timolol maleate 0.5% alone while group B received combination of timolol maleate with Brimonidine tartrate. Results: In group A 3 patients developed acute raise of intraocular pressure despite of  Timolol maleate use while goup B patients who received combination of Timolo maleate and Brimonidine had controlled intraocular pressure. Conclusion: Fixed combination of Timolo maleate 0.5% and Bremonidine tartrate 0.2 % is more effective in controlling of IOP raise in patients undergone Nd-Yag laser capsulotomy for posterior capsular opacification then Timolo maleate0.5% alone.