Open AccessA Study on Adverse Drug Reactions in a Tertiary Care Hospital of South India
Author(s) -
Sherin Shaji,
Mahadevamma Lingaiah,
S Ramesh,
Amal Balakrishnakurup Kovattu
Publication year - 2021
Publication title -
international journal of pharmaceutical sciences review and research
Language(s) - English
Resource type - Journals
ISSN - 0976-044X
DOI - 10.47583/ijpsrr.2021.v71i01.017
Subject(s) - pharmacovigilance , medicine , drug reaction , observational study , adverse drug reaction , adverse effect , health care , pediatrics , drug , emergency medicine , tertiary care , antibiotics , public health , intensive care medicine , pharmacology , pathology , microbiology and biotechnology , economics , biology , economic growth
Medication-related adverse events or adverse drug reactions (ADRs) are harmful events caused by medication. ADRs could haveprofound effects on the patients’ quality of life, as well as creating an increased burden on the healthcare system. ADRs are one ofthe rising causes of morbidity and mortality internationally, and will continue to be a significant public health issue with the increasedcomplexity in medication, to treat various diseases in an aging society. This was a prospective and observational study conducted inmedicine department of sagar hospital, Bengaluru. Patients were enrolled based on the criteria with a suitable statistical tool. Among64 patients, 33 (51.6%) female and 33 (48.44%) were males found. ADRs were more in the age group of 41 – 60, 32 (50%), less in theage group is 0 – 20, 04 (6.25%). Significantly higher numbers of ADRs caused by the antibiotics 25 (39%) followed by antihyperlipidicmic and anti-arrythmic 01 (1.56%), Most of the ADRs were moderate 40 (62.5%) and sever 01 (1.56%) in nature. Mostcommonly affected organ is dermatological system 32 (50%). Majority of the ADRs were associated with antibiotics. Commonly skinrelated ADRs was found in this study. The results provided an insight to the Health care Providers on the importance of monitoringand reporting of ADRs. Our study results emphasize a need for establishing a pharmacovigilance centre to ensure the safe use ofdrugs.