
A Meticulous Review on Coumarin Derivatives as a Marvel Medication for Thousands of Ailments
Author(s) -
Femy Maria K.M,
Delphine Priscilla Antony S,
Amala Babu,
Balakrishnan Nair Vinod,
P. Daisy
Publication year - 2021
Publication title -
international journal of pharmaceutical sciences review and research
Language(s) - English
Resource type - Journals
ISSN - 0976-044X
DOI - 10.47583/ijpsrr.2021.v70i02.030
Subject(s) - coumarin , chemistry , traditional medicine , medicine , organic chemistry
Coumarin derivatives have progressively enticed medicinal chemists because of their potential role in preventing and treatingailments. They epitomize a key motif nucleus in heterocyclic chemistry and a privileged structure in medicinal chemistry because ofits extensive-range pharmacological activity. Regardless of the advancement in medicine over the past century, cancer is still remainthe prominent source of death in the world and it makes indispensible needs to synthesize the compounds with coumarin as the corenucleus. Synthesis of various coumarin derivatives and evaluation of their pharmacological effects can perceive a solution to certainenigmatic demands in health sector. This review article is fixated on different synthetic routes of coumarin nucleus containingcompounds. The review article also highlights different biological activities such as anticancer, antibacterial, anti- inflammatory, antihyperlipidemic and enzyme inhibition activities.