Open AccessA Comparative Study to Assess the Rates on the Recovery of Covid-19 Patients with or without Co-morbidities in Tertiary Care Hospital
Author(s) -
Jaya Prakash K,
P. Sharmila Nirojini,
Neeya Johny,
S Niranjana,
Neenu Wilson,
S Pavithra,
T Nivashini
Publication year - 2021
Publication title -
international journal of pharmaceutical sciences review and research
Language(s) - English
Resource type - Journals
ISSN - 0976-044X
DOI - 10.47583/ijpsrr.2021.v70i02.023
Subject(s) - medicine , comorbidity , diabetes mellitus , copd , population , observational study , covid-19 , dyslipidemia , obesity , disease , infectious disease (medical specialty) , environmental health , endocrinology
Coronavirus disease of 2019 (COVID-19) is a highly contagious infectious disease which lead to a global pandemic. This virus attacksthe small blood vessels, endothelial linings and lead to impaired blood flow and vessel malfunctioning's in various organs. This explainsthe reason why the high vulnerability patient population is those with comorbidities like hypertension, diabetes, COPD, obesity andcardiovascular diseases. The objective of the study was to compare the rates of recovery in the comorbid Covid-19 patient populationwhen compared to those without comorbidities by evaluating their CT Chest - Score, RT- PCR, duration of hospitalization and therebyassess if the quality of life was compromised. A Prospective Observational Study was conducted for a period of 4 months with over400 laboratory-confirmed Covid-19 patients. Out of the 400 patients, considering the exclusion and inclusion criteria 191 moderatelyill covid-19 patients with or without comorbidities were included in the study. The severity of the patients was assessed based on theCT- Chest Score and COVID-19 RT-PCR reports. Various other complications faced by comorbid patients when compared to patientswith nil comorbidities were also investigated. In our study among the underlying comorbidities, the most common were DM (40.11%),HTN (35.32 %), CAD (7.78 %), COPD (6.58 %), CKD (5.38 %) and then hypothyroidism (4.79 %). Our study also concluded that thepercentage of patients with a comorbid condition was higher (59.68%) than those without a comorbid condition (40.31%). The meanreduction in CT-Score in the comorbid and nil-comorbid was found to be 9.38 ± 2.85 and 7.08 ± 2.89. The mean reduction in hospitalstay in the comorbid and nil comorbid group was found to be 9.50 ± 2.34 and 8.08 ± 1.71. The mean reduction in RT-PCR was 10.04 ±2.95 and 7.44 ± 2.33 in the comorbid and nil comorbid group respectively. Therefore, the RT-PCT, duration of hospital stay and CTChest Score showed a statistical si