Open AccessA Review on Benzoxazole Containing Heterocyclic Compounds as a Wonder Medication for Thousands of Ailments
Author(s) -
Femy Maria K.M,
Amala Babu,
Delphine Priscilla Antony S,
Dr.Vinod B,
Dr.Daisy P A
Publication year - 2021
Publication title -
international journal of pharmaceutical sciences review and research
Language(s) - English
Resource type - Journals
ISSN - 0976-044X
DOI - 10.47583/ijpsrr.2021.v70i01.022
Subject(s) - benzoxazole , pharmacophore , chemistry , combinatorial chemistry , pharmacology , organic chemistry , stereochemistry , medicine
The benzoxazole is a heterocyclic aromatic organic compound. It is a vital pharmacophore and honoured structure in medicinalchemistry. It plays a very imperative role with quite useful therapeutic activities such as antiulcers, antihypertensives, analgesic, antiinflammatory, anti-virals, antifungals, anticancer, antidepressant activity, antilishmanial activity, anticonvulsant activity,antitubercular activity, antitumor activity, The review of the literature reveals that the benzoxazole derivatives are marvellouslyeffective compounds and a large number of reviews available for biochemical and pharmacological studies established that theirmolecules are useful against a wide variety of microorganisms. Because of their prominence, the techniques for their synthesis havebecome an attention of synthetic organic chemists. Therefore, in the contemporary review we tried to assemble the chemistry ofdifferent derivative of substituted benzoxazole as well as various pharmacological activities and some of the important methodologies used for the synthesis.