Lupeol Impact on Breast Cancer Management

Conventional therapies for the management of breast cancer are lacking in outcomes and also cause several adverse effects thatprompted the acquisition of new therapeutic approaches for combating breast cancer without any of these pitfalls. Moreover,fostering a holistic therapeutic strategy might be a significant solution to this issue, because it is evident that products obtained viadietary sources have a great number of anti-breast cancer capacities with fewer side effects and low cost. Considerably over the pastdecade, the demand for triterpenes for breast cancer management has increased significantly due to the declining properties ofcancer. However, lupeol (LUP) is a dietary triterpene and the active ingredient found in most medicinal plants has indeed beenwitnessed to manifest numerous pharmaceutical attributes especially anti-cancer activities, and is strongly related to the decliningprevalence of breast cancer in Asian countries. Several reports offer valuable input into the lupeol mechanism of action and therebypropose that this was a multi-target substance with massive potential towards breast cancer (BC) by hitting pivotal molecularpathways associated with breast cancer. There seems to be extensive evidence of such a wonderful compound's anti-breast canceractivity. In this review, we strenuously reaffirm lupeol’s preventive and therapeutic effects in the breast cancer model, with a focuson multi-targeted biological and molecular effects.