Open AccessA Study on Physical and Physiological Impact of Polycystic Ovary Syndrome
Author(s) -
Sathish Kumar B.P,
Sayantan Ghosh,
L.M. Das,
Aksa Merin Jose
Publication year - 2021
Publication title -
international journal of pharmaceutical sciences review and research
Language(s) - English
Resource type - Journals
ISSN - 0976-044X
DOI - 10.47583/ijpsrr.2021.v69i02.022
Subject(s) - polycystic ovary , menstrual cycle , medicine , quality of life (healthcare) , estrogen , hyperandrogenism , disease , gynecology , hormone , pediatrics , physiology , obesity , insulin resistance , nursing
Polycystic ovary syndrome is a relatively common hormonal disorder that causes a number of different symptoms in women ofreproductive age. In such conditions, enlarged ovaries containing multiple small cysts (polycystic ovaries), are found. Although mostwomen with PCOS have polycystic ovaries, some affected women do not. Common to all women with PCOS is an irregularity inmenstrual cycle and the presence of excess male hormones (androgen). It disrupts the functioning of the reproductive organs that produce progesterone and estrogen, the hormones that regulate the menstrual cycle. A prospective observational study was carried out in 125 inpatients, after taking written informed consent from patients those who met the study criteria. A total of 125 patients were enrolled in the study, it was observed that 17.74% have experienced moderate depression, 18.54% patients experienced major irregular menstrual period problem, 2-25% of the patients were dealing with body weight, and 6.45% patients were identified that the growth of visible hair on the upper lip as a major problem. It was also found that 8.87% of patients experienced major menstrual cramps and patients were found worried about PCOS and hence disturbing their quality of life. Various long-term complication and co morbidities have been associated with PCOS and early diagnosed and therapeutic interventions are needed. PCOS is a chronic disease with manifestations across the life span and represents a major health and economic burden. Management should focus on support, education, addressing physiological factors and strongly emphasizing healthy lifestyle with targeted medical therapy as required. Addressing hyperandrogenism is clinically important and monitoring for and managing longer-term metabolic complications including dyslipidemia, IGT, DM2, cardiovascular risk factors, is crucial. Overall, further research is needed in this complex condition.