Open AccessPhytochemical Investigation Using LC-MS Analysis and Antimicrobial Activities of Leaf Extract of Muntingia calabura Linn
Author(s) -
S. Jebaseelan,
B. Edwin Jose,
Dr.R. Meera
Publication year - 2021
Publication title -
international journal of pharmaceutical sciences review and research
Language(s) - English
Resource type - Journals
ISSN - 0976-044X
DOI - 10.47583/ijpsrr.2021.v69i02.006
Subject(s) - phytochemical , petroleum ether , antimicrobial , candida albicans , traditional medicine , chemistry , klebsiella pneumoniae , microbiology and biotechnology , biology , extraction (chemistry) , medicine , chromatography , biochemistry , escherichia coli , organic chemistry , gene
The present study was carried out to determine the possible LC-MS and anti-microbial activity of plant extracts prepared fromMuntingia calabura and phytochemical screening was demonstrated. The extracts from the plant parts like leaf were prepared in different solvents like petroleum ether, chloroform and ethanol. The highest antimicrobial potentials were observed for the ethanolic extracts against (Bacillus subtilis, Staphylococcus aureus, Klebsiella pneumoniae, Pseudomonas aeruginosa, Candida albicans) Its efficacy was comparable to the standard drug, amikacin. Significant amount of tannins, alkaloids, steroids and flavonoids were found. The present study provides evidence that solvent extract of M. calabura contains medicinally important bioactive compounds and this justifies the use of plant species as traditional medicine for treatment of various diseases. Likewise, the leaf extract of Muntingia calabura showed more zone of inhibition with fungus Candida albicans. This shows its antiseptic nature which might have been induced because of the components present.